John T Curnutte Selected Research

4- (cyclopropylamino)- 2- ((4- (4- (ethylsulfonyl)piperazin- 1- yl)phenyl)amino)pyrimidine- 5- carboxamide

1/2019	Efficacy and safety of the dual SYK/JAK inhibitor cerdulatinib in patients with relapsed or refractory B-cell malignancies: Results of a phase I study.
1/2019	Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B-cell Malignancies.

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John T Curnutte Research Topics

Disease

9	Hemorrhage 01/2021 - 06/2015
3	Chronic Granulomatous Disease 08/2008 - 12/2002
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2021 - 01/2019
2	Neoplasms (Cancer) 01/2019 - 01/2019
1	Inflammation (Inflammations) 01/2019
1	Infections 08/2008
1	Crohn Disease (Crohn's Disease) 08/2004
1	Sepsis (Septicemia) 09/2002

Drug/Important Bio-Agent (IBA)

7	Factor Xa (Coagulation Factor Xa)IBA 01/2021 - 01/2016
6	PRT064445IBA 01/2021 - 01/2016
3	AnticoagulantsIBA 01/2020 - 06/2015
3	Factor Xa InhibitorsIBA 01/2019 - 12/2015
2	Hemostatics (Antihemorrhagics)IBA 01/2021 - 01/2019
2	RivaroxabanIBA 11/2020 - 01/2020
2	apixabanIBA 11/2020 - 01/2020
2	4- (cyclopropylamino)- 2- ((4- (4- (ethylsulfonyl)piperazin- 1- yl)phenyl)amino)pyrimidine- 5- carboxamideIBA 01/2019 - 01/2019
2	A-factor (Streptomyces)IBA 01/2019 - 01/2016
2	Janus Kinase InhibitorsIBA 01/2019 - 01/2019
2	Enoxaparin (Lovenox)FDA LinkGeneric 01/2019 - 01/2016
2	CatalaseIBA 08/2008 - 12/2002
1	AntidotesIBA 01/2021
1	edoxabanIBA 01/2018
1	neutrophil cytosol factor 67KIBA 08/2008
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 08/2004
1	Complement System Proteins (Complement)IBA 09/2002

Therapy/Procedure

2	Anticoagulation Reversal 11/2020 - 01/2020
1	Ligation 09/2002
1	Punctures 09/2002